2024 Week 4 NFL Picks, Odds, Best Bets from the Advanced Model: This 5-way football game would pay 25-1

Five teams enter the NFL’s Week 4 schedule with perfect 3-0 records, including the two-time defending Super Bowl champion Kansas City Chiefs. The Chiefs travel west to face the Los Angeles Chargers in an AFC West divisional game on Sunday. With Chargers quarterback Justin Herbert nursing an ankle injury, Kansas City is the 7-point favorite in the latest NFL odds for Week 4. Should you target the Chiefs when making NFL predictions and NFL combo picks for Week 4? Or will Kansas City be the next heavily favored team to suffer a surprise upset loss? Before making any NFL picks or NFL contests in Week 4, be sure to check out the NFL predictions and betting picks from SportsLine’s proven computer model.

The model, which simulates every NFL game 10,000 times, has gained well over $7,000 on top-rated NFL picks since its launch for $100 players. The model entered Week 3 of the 2024 NFL season with an incredible 187-130 run on top-rated NFL picks dating back to the 2017 season. Since Week 7 of 2022, the record for the highest-rated NFL picks is also 41-22.

The model also ranked in the top 10 in straight NFL picks on NFLPickWatch over the past six years, beating more than 94% of CBS Sports’ football pick’em players four times during that period. Anyone who has followed it is way up there.

Now the model has combed through the Week 4 NFL odds and secured five confident NFL best bets. If you use the tips successfully, you can expect a massive payout of around 25:1. You can see the model’s Week 4 NFL picks only at SportsLine.

Top NFL picks of Week 4

After simulating each game 10,000 times, the model is way ahead of the Chicago Bears (-3, 40.5), who have to cover at home against the Los Angeles Rams. The Rams got a win over the San Francisco 49ers, which is nothing to scoff at. However, the 49ers were missing several of their top players (Christian McCaffrey, Deebo Samuel, George Kittle) and the Rams had the advantage of playing at home.

The Rams have also been hit hard by the risk of injury and have to do without wide receivers Puka Nacua and Cooper Kupp. Los Angeles was also a completely different team on the road this season, losing to the Detroit Lions 26-20 and being beaten 41-10 by the Arizona Cardinals. The model covers the bears in this game in almost 60% of the simulations. Check out what other NFL combo picks you can make here.

How to make NFL pays for Week 4

The model also jumped in on four other NFL matchups where the line is said to be way off, including an away underdog winning clearly and defying oddsmakers everywhere. You can see the model’s best bets and stakes in Week 4 of the NFL only at SportsLine.

What are the model’s top NFL picks for Week 4 and what other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the best NFL bets of Week 4 from a model with a 187-130 run on top-rated picks and find out.